ALKBH1-IN-3 prodr_ug

ALKBH1-IN-4 prodr_ug (Compound 29E) is a prodr_ug of a DNA N6-methyladenine demethylase ALKBH1 inhibitor that significantly increases the abundance of 6mA in cells and upregulates the AMPK signaling pathway, thereby inhibiting the viability of gastric cancer cells. ALKBH1-IN-4 prodr_ug exhibits excellent cellular activity and favorable metabolic exposure in vivo, and holds promise for research in gastric cancer.