In the previous article, I mentioned about how omega-3 polyunsaturated fatty acids (n-3 PUFA) affect the T cell signaling in which I have described n-3 PUFAs mediated T cell Receptor activation and downstream signaling. Now, I will describe how omega-3 polyunsaturated fatty acids affect T cell …
Researchers have found a molecular link between the omega-3 polyunsaturated fatty acids (n-3 PUFA) and signaling involved in the T cell (T lymphocytes) maturation and differentiation. T lymphocytes such as CD4+ cells are the immune cells that circulate throughout the body and defend the host organism …
What is niacin? Niacin is an organic acid the IUPAC name of which is pyrimidine-3-carboxylic acid. It is also called as nicotinic acid or vitamin B3. However, the biologically active form is nicotinamide, not the niacin which is formed during the formation of niacin-derived cofactors …
Protein Data Bank or PDB is an online computer-based directory that contains the crystal structure of biological macromolecules such as proteins and nucleic acids along with the supplementary information about the source of the macromolecule and how it was obtained, resolution of the diffraction data and …
Biochempages
Enzymes
December 23, 2015
Angiotensin II from Angiotensinogen Angiotensin is a group of peptide hormones that contains mainly four types; I, II, III, and IV. However, the biologically active form is angiotensin II. All of these are produced from the single precursor protein angiotensinogen in different steps. Angiotensinogen is a …
Biochempages
Cancer
December 21, 2015
Mitochondrial metabolism Mitochondrial metabolism constitutes central metabolism of the where end products of the glucose, amino acids and fats are catabolized through different routes and funneled into the citric acid cycle. Mitochondria are the powerhouse of the cell where most of the ATPs, the energy currency …
Biochempages
Cancer
December 21, 2015
Researchers have found a new approach treating growth factor receptor (FGFR4) associated cancer that recruits STAT3 and activate and express cell growth and proliferation-associated genes. All human beings have 99.9% similar genetic material, but they have 0.1% dissimilar genetic makeup. Yes! Only a 0.1 % difference …
Biochempages
Cancer
December 17, 2015
A team of researchers performed quantitation of N-glycans from the human alfa-acid glycoprotein (haGP) that revealed N-glycans as potential biomarkers for pancreatic cancer. hAGP is an N-linked glycoprotein (single polypeptide) with 183 amino acids and molecular weight 41 kDa. hAGP contains about 45 % of carbohydrate …
Researchers have worked out on the bioavailability of selenium (Se) and its implication for animal agriculture. Se is a trace element that is essential for the growth and development of the immune system and metabolism. However, it does not work alone but it gets incorporated into …
According to a recent study, interleukin-22 can promote stem-cell-mediated regeneration of the intestinal epithelium. The present study was carried out by a team of researchers and has been published on Nature. The generation of the epithelial layers is one of the critical problems that prevent the …
