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New opportunity for biochemistry Ph.D. graduates. Case Western Reserve University, Cleveland, Ohio, USA has announced postdoctoral position for the Ph.D. graduates of biochemistry or related fields. The postdoctoral position is based on pharmacology, Biochemistry and Biomedical Sciences.
The project is based on cell biology; how a cell can defend the integrity of the nuclear DNA? The DNA molecule of the cell itself is a blueprint of life that makes the cell to perform its fundamental processed by expressing different proteins and enzymes that can further be involved in different processes to keep cell survive.
DNA contains many chemical constituents and moieties that are actively involved in different processes and allow the DNA itself to change according to the environment. Such changes and modifications lead to the change in the double-helical structure of the DNA that ultimately leads to the abnormal or lethal endpoint of the affected cells such as in the initiation of cancer, premature aging, and neurodegenerative diseases.
Throughout the evolution, the signaling pathways that are responsible for the initiation of the repair of damaged DNA have been overlaid. DNA damage can arise due to the environmental stresses (such as UV light irradiation) and cellular activities (such as the formation of free radical species). And the signaling pathways responsible for the initiation of repair of DNA damage is called as DNA damage response.
Therefore, selected candidates will have to use pharmacological and biochemical tools along with structural and genetic tools to understand the molecular aspect of DNA damages and translating them into different therapeutic strategies that can be utilized against human cancers.
Candidates with a Ph.D. degree from biochemistry and related biological sciences with the strong background of biochemical tools including western blotting, immunoprecipitation, and immunofluorescence, molecular techniques such as PCR, cloning, and vector generation, and cellular techniques such as cell culture, transfection are highly encouraged to apply.
Interested candidates with qualifications as mentioned above can apply for this position by sending an email to the principle investigator Dr. Youwei Zhang at yxz169(at)case.edu. Alternatively, you can also apply to this position through this link jobs.sciencecareers.org
Department of pharmacology, Case Comprehensive Cancer Center
Case Western Reserve University
Cleveland, Ohio, USA